Prognosis
Covid Doctors Find a Turning Point in Life-Threatening Cases
- Research hints antiviral interferon could help some patients
- Brothers with rare gene defects point way to possible therapy
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When two brothers fell critically ill with Covid-19 around the same time in March, their doctors were baffled. Both were young -- 29 and 31 years old -- and healthy. Yet within days they couldn’t breathe on their own and, tragically, one of them died.
Two weeks later, when a second pair of Covid-stricken brothers, both in their 20s, also appeared in the Netherlands, geneticists were called in to investigate. What they uncovered was a path leading from severe cases, genetic variations, and gender differences to a loss of immune function that may ultimately yield a new approach to treating thousands of coronavirus patients.